Medical Rounds

November/December 2002

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LET THEM EAT BREAD: An estimated one in 200 Americans suffer from celiac sprue, or gluten intolerance. If they eat foods containing wheat, rye or barley, they can suffer severe, even fatal, intestinal damage. In the September 27 issue of Science, researchers working with chemistry and chemical engineering professor Chaitan Khosla identify the cause of the disease, a fragment of gluten that resists digestion. Next up: testing treatment with peptidase, a dietary enzyme made by a bacterium.

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